ManUp Girth BioMatrixEx™ enhances traditional hyaluronic acid girth treatment by combining immediate volume with regenerative exosome technology. In this procedure, HA filler provides instant circumference enhancement while JuveXO® exosomes are introduced to support tissue health, vascular signaling, and cellular activity within the treated area.
JuveXO® exosomes contain up to 50-100 billion growth factors and cytokines per milliliter. These biologically active signals help promote collagen production, support tissue recovery, and improve overall skin integrity. When layered with HA filler, this dual-action approach focuses not only on size but also on optimizing tissue quality and performance.
For many patients, BioMatrixEx™ offers a powerful combination of immediate enhancement and advanced regenerative support.






ManUp Girth BioMatrixEx™ is an advanced regenerative girth enhancement designed to combine immediate circumference improvement with next-generation cellular support. This innovative treatment pairs hyaluronic acid filler for instant volume with JuveXO® exosome technology to help optimize tissue health and performance.
The result is a dual-action treatment focused not only on size, but also on improving tissue health, structural integrity, and long-term performance.
Upgrade your results with regenerative performance enhancement.
ManUp Girth BioMatrixEx™ is an advanced girth enhancement procedure that combines hyaluronic acid filler with regenerative JuveXO® exosome technology. The HA filler provides immediate volume while the exosomes support tissue regeneration, collagen production, and overall tissue health.
JuveXO® exosomes contain billions of growth factors and signaling molecules that help stimulate cellular activity, promote collagen production, and improve tissue quality. When combined with HA filler, they enhance the regenerative environment of the treated area.
Patients typically see immediate girth expansion from the hyaluronic acid filler. Over the following weeks, the regenerative benefits of the exosomes help support tissue recovery, collagen development, and improved structural integrity.
The hyaluronic acid component provides immediate results that gradually absorb over time. The regenerative support from exosomes may help improve tissue quality and support longer-lasting overall outcomes.
ManUp Girth ExoBoost™ is performed by trained medical professionals using clinically developed materials. As with any injectable procedure, minor swelling or bruising may occur temporarily. A consultation is required to determine if the treatment is appropriate for you.
Men who want girth enhancement along with regenerative tissue support may be ideal candidates. This treatment is particularly appealing to those seeking both immediate volume and improved tissue health.
Non-surgical male enhancement designed to increase girth, improve firmness, and restore peak performance.
All in a discreet, physician-guided setting.