ManUp Girth BioMatrix™ is our advanced dual-phase girth enhancement treatment designed to increase penile circumference while providing greater structural support over time. This proprietary approach combines hyaluronic acid for immediate volume with PMMA microspheres that stimulate your body’s natural collagen production.
While traditional HA fillers gradually dissolve over time, BioMatrix™ works differently. The PMMA component forms a supportive collagen scaffold beneath the skin. As your body produces new collagen around the microspheres, the structure helps reinforce girth gains while maintaining a natural look and feel.
The result is a more durable enhancement designed for men who want increased firmness, stability, and longevity beyond standard filler treatments.
ManUp BioMatrix™ combines premium hyaluronic acid with advanced PMMA microspheres to create a structural support matrix designed for immediate enhancement and long-term collagen support. This advanced procedure delivers natural-looking volume, improved contour, and long-lasting aesthetic results.
A natural regenerative option for men Perfect for men seeking a meaningful increase in girth with a smooth, natural appearance and long-term structural support.
improved function and performance within weeks.
Designed for men seeking greater circumference, improved contour, and a more dramatic yet natural-looking enhancement.
Our most comprehensive BioMatrix™ treatment for men seeking maximum girth, exceptional contour, and long-lasting structural support with premium HA/PMMA technology.






ManUp Girth BioMatrix™ is an advanced girth enhancement treatment designed to increase penile circumference while providing stronger structural support over time. This proprietary dual-phase approach combines hyaluronic acid for immediate expansion with PMMA microspheres that stimulate natural collagen production.
This innovative treatment is ideal for men seeking increased firmness, improved stability, and longer-lasting results beyond standard filler procedures.
Say hello to stronger structure and longer-lasting girth.
Traditional HA fillers provide temporary volume that gradually dissolves. BioMatrix™ combines HA with PMMA microspheres, which stimulate your body to produce collagen, creating a longer-lasting internal support structure.
The HA component gradually absorbs over time. However, the PMMA microspheres remain in place and stimulate collagen production, resulting in long-term structural enhancement. Longevity varies based on individual biology.
When performed by a trained and certified provider, BioMatrix™ follows strict medical protocols. As with any injectable treatment, temporary swelling or bruising may occur. A consultation is required to assess candidacy and suitability.
You will notice immediate expansion from the HA component. Over the following weeks and months, collagen production increases, enhancing firmness and structural integrity.
Men seeking longer-lasting girth enhancement, increased firmness, and structural support beyond traditional fillers may be ideal candidates. A private consultation determines if BioMatrix™ is appropriate for your goals.
Non-surgical male enhancement designed to increase girth, improve firmness, and restore peak performance.
All in a discreet, physician-guided setting.